The utility model discloses a medical device box, which comprises a box cover (1), a box body (2) and a box bottom (3) which are of a split structure, wherein partition plates (4) are arranged in the box body (2), and disinfection holes are arranged at the bottom of the box body (2); and handles (6) are arranged at the sides of the box body (2). The medical device box has the advantages that: medical devices can be sorted and placed in the box body, the efficiency is high, and a disinfectant is not easily attached to the skin; and the secondary pollution can not be generated.