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发明公开
CN1951432A 参附组合物、制剂及其制备方法和用途 失效 - 权利终止 转让

参附组合物、制剂及其制备方法和用途
摘要：
本发明提供了一种新的参附组合物，该组合物中附子总生物碱的含量大于等于50％，本发明中提供的参附组合物质量可控，稳定性好，药理作用明显优于已上市的参附注射液。其中附子生物碱提取物是将附子进行特殊处理，水解附子中的双酯类乌头碱，使其转化为毒性很低的醇氨类生物碱。本发明提供了参附组合物在制备治疗感染性休克、失血性休克、心源性休克方面的应用。
摘要（英）：

The invention discloses a pharmaceutical composition of ginseng and monkshood, wherein the content of monkshood alkaloid is not lower than 50%. The pharmaceutical composition provided by the invention has the advantages of controllable quality, better stability, and improved pharmacological actions. The monkshood alkaloid extract is prepared through specially treating monkshood, hydrolyzing di-ester aconitine in monkshood so as to convert it into low-toxicity alkaloid. The obtained composition can be used for treating infectious shock, bleeding shock and cardiogenic shock.

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