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发明授权
CN1852736B 免疫球蛋白嵌合单体-二聚体杂合体 失效 - 权利终止

免疫球蛋白嵌合单体-二聚体杂合体
摘要：
本发明涉及嵌合单体-二聚体杂合体蛋白，其中所述蛋白包含第一和第二多肽链，所述第一多肽链包含至少一部分免疫球蛋白恒定区和生物活性分子，所述第二多肽链包含至少一部分免疫球蛋白恒定区，不含第一链的生物活性分子。本发明还涉及本发明嵌合单体-二聚体杂合体蛋白的使用方法和制备方法。
摘要（英）：

The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.

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