This invention provides an intravenous injection approvable anthracene-nucleus antineoplastic-antibiotic nanomicelle drug, which comprises anthracene-nucleus antineoplastic antibiotic, macrogol derivelized phosphatide those have therapy dose, and findings acceptable in medicine. In the nanomicelle, the macrogol wraps around the drug hydrophobilic nucleuses and forms hydrophilic protective layer, this can provide the drugs from contacting with proteins in blood and identifying and licking up by esoderma system in body, so the drug cycle time in body will be prolonged.