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CN1811432A 一种筛查系统性硬化症疑似患者血清的方法及其专用多肽 失效 - 权利终止

一种筛查系统性硬化症疑似患者血清的方法及其专用多肽
摘要：
本发明公开了一种筛查系统性硬化症疑似患者血清的方法及其专用多肽。本发明的筛查系统性硬化症疑似患者血清专用多肽，是具有序列表中序列1和/或序列2的氨基酸残基序列的多肽。筛查系统性硬化症疑似患者血清的方法，是用具有序列表中序列1和/或序列2的氨基酸残基序列的多肽作为抗原，用ELISA方法检测待测血清中的抗具有序列表中序列1和/或序列2的氨基酸残基序列的多肽的抗体水平。如果待测血清中的酶底物显色反应的光密度值高于X+2SD，则待测血清为系统性硬化症疑似患者血清；所述X+2SD中，X为正常人血清中的酶底物显色反应的光密度平均值，2SD为正常人血清中的酶底物显色反应的光密度值的二倍标准差。
摘要（英）：

The present invention discloses a method for screening systemic sclerosis borderline case patientí»s serum and its special-purpose polypeptide. Said special-purpose polypeptide is the polypeptide having amino acid reside sequence of sequence 1 and /or sequence 2 in sequence table. The described screening method is characterized by that it uses the above-mentioned polypeptide as antigen, and utilizes ELISA method to detect the level of antibody for resisting the polypeptide having amino acid residue sequence of sequence 1 and /or sequence 2 in sequence table in the serum to be tested. Besides, said invention also provides the concrete steps of said screening method.

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