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发明公开
CN1748769A 治疗血管神经性头痛药物的制备方法 有权 许可

治疗血管神经性头痛药物的制备方法
摘要：
本发明涉及一种中药的制备方法，具体是治疗血管神经性头痛药物的制备方法。它包括以下步骤：取规定量的川芎、白芷、藁本、细辛加水5－12倍量，蒸馏提取挥发油，水液a及药渣b备用；取规定量的丹参、葛根、天麻加50－90％乙醇6－12倍量，回流提取1－4次，每次1－4小时，合并提取液，浓缩，制成干浸膏c，药渣d备用；药渣b与药渣d合并，加水4－10倍量，煎煮1－4次，每次1－4小时，合并煎液及水液a，离心分离，取上清液，浓缩，制成干浸膏备用f；制得挥发油与水牛角浓缩粉、猪脑粉混匀，与干浸膏c、干浸膏f混合，粉碎成细粉，制成药剂。所述的药剂为片剂、胶囊剂、颗粒剂、丸剂等临床使用的剂型。具有用量少、生物利用度高和临床用药安全。
摘要（英）：

The present invention relates to a Chinese medicine, and especially the preparation process of medicine for treating angioneurotic headache. The preparation process includes the following steps: distilling Chuanxiong rhizome, white atractylodes rhizome, Chinese ligusticum and asarum herb with water to obtain volatile oil, decoction A and dreg B; alcohol reflux extracting red sage, kudzu vine root and gastrodia tuber, and concentration to obtain extractum C and dreg D; merging dreg B and dreg D, decocting and merging the decoction and decoction A, centrifuging to separate, taking supernatant, and concentrating to obtain extractum F; mixing the volatile, concentrated buffalo horn powder, pig brain powder, extractum C and extractum F, grinding and preparing into medicine preparation, which may be tablet, capsule, granule, bolus, etc. The present invention has the features of small dosage, high bioavailability and clinical safety.

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