The embodiment of the invention discloses a high-efficiency three-dimensional animation production method. The method comprises the following steps: step 100, designing an original painting; step 200,manufacturing a three-dimensional animation material; step 300, performing Layout lens rehearsal based on the manufactured material to capture character features, and completing manufacturing of a three-dimensional animation; and step 400, synthesizing and correcting colors of the three-dimensional animation, editing and mixing sound, and outputting a slice. The method is based on a role intelligent generation engine, identical topology UV technology, material mapping technology, an one-key binding system, an one-key expression system, a dynamic lens snapshot system, a mouth shape intelligentgeneration system, a motion capture, expression motion capture and dynamics simulation system, a GPU physical illumination and other advanced technologies. The technical bottleneck of the three-dimensional animation is greatly reduced, production efficiency of three-dimensional animations is greatly improved, and manufacturing cost is reduced.