A matter hoisting trace planning system for hoisting work in an obstacle space comprises a positioning base station, wherein positioning labels are arranged on a barrier and a hoisting matter; the positioning base station is connected to a coordinate calculating module and is used for transmitting data to the coordinate calculating module in real time; the coordinate calculating module is used forcalculating real-time coordinates of the barrier and the hoisting matter; the output end of the coordinate calculating module is connected to the input end of a hoisting matter transportation route planning module; and the output end of the hoisting matter transportation route planning module is connected to the input end of a crane control module. The invention aims at providing a system which is applicable to transportation route planning in hoisting work and is capable of reducing energy consumption, improving working efficiency and enabling a field controller to obtain the hoisting mattertransportation condition in real time, and a use method thereof.