The invention discloses a multi-scale porous scaffold design method based on a three-cycle minimum curved surface. The method comprises the following steps: respectively inputting a function expression, a bias thickness, a triangularization minimum triangle angle and a maximum triangle side length of a four-stage three-cycle minimum curved surface; generating a layered filling area of the first-level three-cycle minimal curved surface to obtain a layered filling area of the macroporous structure; generating a layered hole region of the secondary three-cycle minimal curved surface, and calculating a layered filling region of the mesoporous structure; generating a layered filling area of the three-stage three-cycle minimal curved surface to connect the separation entity into a whole, and generating a layered filling area of the additive manufacturing mesoporous structure; generating a layered hole region of the four-stage three-cycle minimal curved surface, and calculating a layered filling region of the microporous structure; and finally outputting the layered filling area of the multi-scale porous scaffold. The method is stable, reliable, accurate and efficient, complex multi-scaleporous design is carried out in a two-dimensional plane, and the consumption of computing resources is reduced.