The invention provides a pyridine-containing compound, relating to the field of medicines. The chemical structure of the compound is shown as in a formula I: The formula I is shown in the description.The compound can be taken as an inhibitor of cyclooxygenase 2 for treating inflammation. The invention further provides an extration method of the compound for preparing the pyridine-containing compound which has the effect of inhibiting cyclooxygenase 2 and has application value in the aspect of inflammation-related diseases.