The invention discloses a metal mine blind shaft pre-grouting engineering chamber group arrangement mode. The method comprises the following steps that (A) grouting chambers are arranged; (B) drillingchambers are arranged; and (C) full-S-hole construction is adopted. An existing roadway is used for arranging a grouting chamber; meanwhile, the stability in the drilling and grouting process is improved through the three drilling chambers built around the 112-line blind shaft and the structural layout in the drilling chambers, and through verification of following drilling and grouting construction, the remaining water inflow of the shaft obtained after construction grouting is about 4.83 m < 3 >/h, and the qualified standard of a construction contract is met.