The invention discloses a self-floating navigation mark adapted to large water level amplitude variation, comprising a base(1) fixed to the foundation by an anchor rod (11), a guide rod (2) is arranged on the base (1), a sheath (3) is fixed on the outer side of the guide rod (2) , a guide rail (33) is arranged on the sheath (3), a floating body platform (4) is arranged on the sheath (3), a throughhole is arranged at one end of the floating body platform (4), a navigation mark (5) is fixedly arranged at the other end, the through hole is sleeved on the sheath (3), a roller group is arranged inthe through hole, and a first counterweight cabin group and an annular cabin structure are arranged in the floating body platform (4). The invention adjusts the balance of the floating body platformin the water flow by the buoyancy of the floating body platform itself and the counterweight block, and then combines the sliding connection of the roller on the guide rail to achieve the purpose thatthe floating body floats steadily with the water level at a fixed position, and the floating body has simple and compact structure, convenient installation and convenient operation.