The invention provides a rubber tree HbWRKY82 gene. The nucleotide sequence of the gene is as shown in SEQ ID NO:1. The invention further provides HbWRKY82 gene-coded protein and application of the gene. Accordingly, the HbWRKY82 gene is obtained through cloning in a rubber tree for the first time, the gene has the transcription factor function and is located in a cell nucleus, the expression of the gene is induced by ethephon, the expression is lowered in the leaf senescence process in a rubber tree with dead bark, and the reverse regulation function is achieved. After overexpression, tolerance of transgenic plants on stress environments such as high salt and drought; meanwhile, the function of regulating leaf senescence is achieved, and the important regulating effect is achieved in growth and development of the rubber tree and response to organism and microorganism adversity stress. In the future, the plants are subjected to genetic improvement by means of the HbWRKY82 gene, and effective gene resources can be provided for stress resistance such as plant salt resistance and drought resistance and delaying leaf senescence.