The invention provides a device and a technique for integrally preparing a base material and an inner surface metallized circuit based on 3D printing. The device comprises a mechanical arm system, a 3D printer and a sliding rail system. Through the principle, based on the 3D printer, printing forming is carried out on an antenna base material structure by using an ink jet printing head or a melt extrusion head, working position switching is carried out on a printing platform integrally by using sliding rails in the process of printing the antenna base material, the mechanical arm system is used for stretching an ink jet head into a formed base material frame cavity on a first working position, a printing function is started after a printing nozzle is controlled to be adjusted in the normaldirection of the inner surface of a base material frame, a designed metal circuit pattern is sprayed and printed on the inner surface of the formed base material according to a predetermined trajectory, after the spraying and printing of the pattern, the printing platform is witched to a second working position through the sliding rails, the printing of a base material model is recovered, and then circulating printing of two processes is carried out to finally complete integral forming of the inner surface circuit structure. Rapid manufacturing for a conformal antenna, an inner wall hook facecircuit pattern and the like can be realized.