The invention discloses a method for dissolving an extracellular matrix of a candida albicans biofilm. The method comprises the following steps: adding an enzyme solution to a bacterial solution, thenallowing a reaction for 1.5 to 2.5 hours at 25 DEG C, centrifuging to discard the enzyme solution after completing the reaction, then adding a sodium houttuyfonate solution, adding an XTT solution after lasting the reaction for 20 to 28 hours at 37 DEG C, and then lasting the reaction for 1.5 to 2.5 hours at 37 DEG C in the dark; the bacterial solution is the bacterial solution of candida albicans which produces a biofilm. Sodium houttuyfonate is an addition extract of Chinese herbal medicine herba houttuyniae. By utilizing the synergistic action of the sodium houttuyfonate and enzyme, components of the extracellular matrix of the candida albicans biofilm are directionally hydrolyzed, thereby effectively improving the antibacterial effect.