The invention relates to a silicone rubber-based wear-resistant conductive graphene printing ink. The silicone rubber-based wear-resistant conductive graphene printing ink comprises, by mass, 100 parts of silicone rubber, 1-5 parts of an air-oxidizing unsaturated organic compound, 200-500 parts of a volatile organic solvent, 0.01-1.5 parts of a catalyst, 1-10 parts of a crosslinking agent, 0.2-3 parts of an adhesive additive, 0.2-3 parts of an adhesion promoter and 10-100 parts of coated graphene. The graphene is one or more of monolayer or multilayer graphene having a diameter of 0.001-5 [mu]m. The invention also provides a method for preparing the graphene conductive ink. The preparation method has the advantages of simple preparation steps and low cost, and the ink has the advantages ofgood stability, excellent electrical conductivity and good fluidity; and the ink has good mechanical properties, moldability, adhesion, impact resistance, wear resistance and scratch resistance afterbeing formed. The graphene is coated with silicone resin, and the silicone resin for coating treatment includes one or more of methylphenyl silicone resin, vinyl silicone resin and hydromethylsilicone resin, so the mechanical properties and the dispersion stability of the graphene in the ink are improved.