The invention discloses a treatment process for an arsenic sulfide containing material. The treatment process for the arsenic sulfide containing material comprises three main steps: pulpifying of theraw material, oxygen pressure acid leaching, and reducing and separating. The liquid-solid mass ratio is 3:1 to 10:1 in the pulpifying of the raw material, the pulpifying lasts for 2-4 hours at the temperature of 80-100 DEG C; the oxygen pressure acid leaching lasts for 2-4 hours at the temperature of 90-180 DEG C at the pressure of 0.1-3 MPa at the speed of 100-3000 r/min; an arsenic containing leaching agent is reduced and separated through sulfur dioxide, sodium thiosulfate or sulfite, and is then secondarily pulpified and separated to obtain a sulfite product. The arsenic content in a leaching residue is less than 5%, the recovery rate of arsenic is more than 80%; a surfactant is added in the pulpifying process, so that the oxidation reaction is more thorough; a vacuum pulpifying tankprovided with an exhaust system is used to prevent the waste gas from overflowing, and is beneficial for improving the operation environment. The technological process is short, and the treatment process has the advantages of environmental protection, economical efficiency, energy saving, and efficient utilization of resources, etc.