The invention discloses a method for controlling and restoring filler biological clogging of a constructed wetland. The method comprises the following steps that (1) a polysaccharide enzyme solution is prepared, and alpha-glucose hydrolytic enzyme, beta-dextranase and alkaline protease are collocated at the proportion of (3-5):(3-5):(1-3) respectively; and (2) the prepared polysaccharide enzyme solution in step (1) is added into the constructed wetland, and the addition concentration is 10-25mg/l. The method for controlling and restoring filler biological clogging of the constructed wetland isrelatively safe to the environment and addition personnel, the ecological system in the wetland cannot be damaged, the effluent purification effect cannot be affected, the addition dosage is small, the cost is low, the effect is good, the desired effect can be produced quickly, and the permeability coefficient can be restored to be 10 times or above.