The invention discloses a preparation method and an application of low-dielectric loss piezoelectric ceramic materials. The method includes the steps: mixing silicon nitride, aluminum oxide and molybdenum disulfide, ball-milling mixture and placing the ball-milled mixture into ethylene glycol; adding bisphenol-A epoxy resin, strontium zirconate and polyether propylene oxide, and stirring and heating mixture to obtain thermal reaction mixed liquid; ageing the thermal reaction mixed liquid, adjusting pH (potential of hydrogen) of the mixed liquid, and drying the mixed liquid to obtain ceramic slurry; performing curing and demolding on the ceramic slurry in molds to obtain blanks; sintering the blanks to obtain the low-dielectric loss piezoelectric ceramic materials. The prepared low-dielectric loss piezoelectric ceramic materials are high in mechanical quality factor and electromechanical coupling coefficient and low in dielectric loss and have good application prospects in electronic device products.