The invention discloses a preparation method of a 4-ethyl aminobenzoate powder. The preparation method includes the steps of: 1) catalytically hydrogenating 4-nitrobenzoic acid to prepare 4-aminobenzoic acid; 2) esterifying the 4-aminobenzoic acid with ethanol to prepare a 4-ethyl aminobenzoate crude product; 3) performing ethanol recrystallization, in the presence of alkyl sulfonate, to the 4-ethyl aminobenzoate crude product to prepare the 4-ethyl aminobenzoate powder. In the method, a less amount of alkyl sulfonates, such as sodium dodecyl sulfate, is added during the ethanol recrystallization step, so that the crystallization process of the product is controlled well. The 4-ethyl aminobenzoate powder has small granularity and uniform granularity distribution, is high in quality, and can satisfy the high demand on granularity in the fields of medicines, materials and cosmetics.