The invention discloses a quick-release mounting system for mounting a panel instrument, such as a video monitor, to a mounting surface or support, such as a seatback or other structure. The mounting system comprises one or more mounting mechanisms configured to be mounted to the mounting surface or support. Each mounting mechanism has a locking member coupled to a first main body. The locking member is movable between a locked position in which the locking bolt engages a retaining stud mounted to the back surface of the panel instrument thereby locking the mounting mechanism to the first retaining stud and an unlocked position in which the locking member is disengaged from the first retaining stud. The mounting mechanism also has a cam shaft having a cam fixed in rotation with the cam shaft. The cam is operably coupled to the locking member such that rotation of the cam shaft moves the locking member between the locked and unlocked positions.