The invention discloses an iOS-based defense method for masque attacks of an application, and belongs to the field of mobile intelligent operation system security. By utilizing a cooperative effect between an authentication mechanism and an exclusive private key, masque attacks in different forms are prevented. A protective mechanism prevents attack means, including replay attack and non-verified application updating, commonly used in two masque attacks. By implementing the method, a practical and easy-to-implement solution can be provided for the masque attacks.