Disclosed is a slurry shield full-automatic pipe replacement crane. The slurry shield full-automatic pipe replacement crane comprises a trailer and a pipe replacement crane mechanism. The pipe replacement crane mechanism is installed on the trailer, and a pipe storage mechanism is arranged on the trailer. The pipe replacement crane mechanism comprises a pipe replacement crane longitudinal beam, wherein the pipe replacement crane longitudinal beam is connected with the trailer. A longitudinal translation oil cylinder is arranged on the pipe replacement crane longitudinal beam, and a travelling frame is connected to the stretching and drawing end of the longitudinal translation oil cylinder. A crane transverse beam frame and a transverse translation oil cylinder are arranged on the travelling frame, one end of the transverse translation oil cylinder is connected with the crane transverse beam frame, and the other end of the transverse translation oil cylinder is connected with the travelling frame. An electric hoist is arranged on the crane transverse beam frame, and moves along the crane transverse beam frame. A tank chain groove is formed in the top of the travelling frame, a tank chain groove is also installed in the lower surface of a platform on the top of the trailer, and the two tank chain grooves are connected through a tank chain. The slurry shield full-automatic pipe replacement crane is simple in structure and high in practicability, is successfully put into use, reduces the labor intensity of workers in the slurry pipe replacement process, and greatly improves the working efficiency.