The invention relates to a lucid ganoderma oral liquid and a preparation method thereof. The lucid ganoderma oral liquid is prepared from: lucid ganoderma, ginseng, cordyceps militaris, DHA powder, stevioside, MACA, soybean peptide, burdock and astragalus membranaceus. The lucid ganoderma oral liquid has the following advantages: 1) the oral liquid is produced through superfine grinding technology, so that all active components in the lucid ganoderma, ginseng, cordyceps militaris, MACA, burdock and astragalus membranaceus are completely maintained, and a bitter taste of the lucid ganoderma is eliminated, dietary value of the medicine components are fully achieved, and the oral liquid has scientific and reasonable formula, is balanced and complemented in property and flavor and achieves addition of effects; 2) the oral liquid can improve immunity and endocrine regulation capability, and can accelerate body metabolism and induce generation of interferon, thereby achieving anti-cancer effect, and meanwhile, the oral liquid can treat tumors and is safe and toxic-free, is suitable for people for drinking for a long time, especially, for diabetic patients; and 3) by means of the oral liquid, body physique is improved and disease resistant capability is improved, removal of virus by immune system is promoted and recovery of patients is improved.