The invention relates to a method and a device realizing shunting route control by combining STP and CTC. The method comprises the steps of: 1) an STP system receives a shunting service list, calculates a shunting route according to current locomotive position information and a shunting service destination and initializes a shunting route application as route setting is required; 2) a CTC system receives shunting route application information from the STP systems of all locomotives in real time to establish a shunting route application form or insert a newly received shunting route application form into the shunting route application form; 3) the CTC system receives the shunting service list from a shunting planning server of a station for all the locomotives in real time; and 4) the CTC system operates the shunting route applications in the shunting route application form. Compared with the prior art, the labor intensity of train operation staff is reduced, and the shunting service efficiency is improved. The shunting route is safely controlled by virtue of the equipment, so that the problem of mismanagement of shunting route is fundamentally avoided.