The invention discloses a method for preparing azabicyalo compounds by efficient catalysis of o-aminobenzenesulfonic acid and zirconocene Lewis acid. The method takes 2-cyclohexene-1-ketone, aromatic aldehyde, and arylamine as raw materials, takes ethanol as a solvent, and takes zirconocene dichloride as a catalyst; under condition that Bronsted acid- o-aminobenzenesulfonic acid is added, the zirconocene dichloride can prepare a series of azabicyalo compounds with high efficiency and high yield. The catalyst has the advantages of little amount, low cost, no toxicity, stabilization on air, mild reaction condition, and high atom economy, after a reaction is complete, the product is subjected to simple separation and recrystallization to obtain the azabicyalo compound. The preparation of the azabicyalo compound opens up a novel approach of low cost, and environmental protection and high efficiency, and has wide application prospect.