The invention discloses a full-automatic paper change inserted rod device of an offset press. The full-automatic paper change inserted rod device of the offset press comprises a frame, wherein the frame is formed by a left installation plate, a right installation plate, an inserted rod hole plate provided with through holes and a locating baffle in a surrounding manner. The ends of a row of inserted rods correspond to the through holes sequentially, and the other end of each inserted rod of the row of inserted rods is fixed to an inserted rod pushing plate. A left inserted rod moving threaded rod is arranged in the frame and close to the left installation plate, and a right inserted rod moving threaded rod is arranged in the frame and close to the right installation plate. One end of each of the left inserted rod moving threaded rod and the right inserted rod moving threaded rod is connected with the inserted rod hole plate, and the other ends of the left inserted rod moving threaded rod and the right inserted rod moving threaded rod both sequentially penetrate the inserted rod pushing plate and the locating baffle and then are connected with a left transmission chain wheel and a right transmission chain wheel correspondingly. An inserted rod motor drives the left inserted rod moving threaded rod and the right inserted rod moving threaded rod to rotate through linkage chains. Rectangular frame overturning mechanisms are arranged on the outer side wall of the end, close to the inserted rod hole plate, of the left installation plate and the outer side wall of the end, close to the inserted rod hole plate, of the right installation plate. Each rectangular frame overturning mechanism comprises a guide rod groove. The end of a guide rod clamped into the guide rod groove of each rectangular frame overturning mechanism is connected with a taking-up and paying off motor through a rotating shaft. Lifting sleeves arranged on the guide rods in a sleeving manner are provided with locating rod frames connected with a paper holder of the press. Lifting wheels are arranged on the portions, above the locating rod frames, of the lifting sleeves, and the lifting wheels drive the rectangular frame to ascend and descend through transmission assemblies.