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发明公开
CN106265717A 狗肝菜多糖在制备防治糖尿病药物或保健品中的应用 失效 - 权利终止

狗肝菜多糖在制备防治糖尿病药物或保健品中的应用
摘要：
本发明公开狗肝菜多糖在制备防治糖尿病药物或保健品中的应用。通过制备糖尿病动物实验，发现其能够可改善糖尿病大鼠的症状，抑制死亡，维持体重，降低血糖和提高耐糖量，显示其良好的降糖作用。此外，狗肝菜多糖能够降低糖尿病大鼠血清糖基化终产物-肽( AGE-P )、糖化血红蛋白(HbAlc)、总胆固醇（TC）、甘油三酯TG）、低密度脂蛋白（LDL-C）和肾脏醛糖还原酶AR）活性或含量，升高肝糖元和高密度脂蛋白HDL-C）含量，说明其通过抑制肝脏、肾脏病变和改善血脂环境，达到抑制糖尿病并发症的作用。通过实验证明狗肝菜多糖具有较好的防治糖尿病及其抑制并发症作用，这种新用途为其药用价值开拓了新领域，具有重要的应用价值和经济效益。
摘要（英）：

The invention discloses application of dicliptera chinensis polysaccharide in preparation of drugs or health-care products for preventing and treating diabetes. It is found through an experiment of a diabetic animal that the dicliptera chinensis polysaccharide can improve the symptoms of a diabetic rat, inhibit death, maintain weight, lower blood sugar and improve sugar tolerance and hasa good hypoglycemic effect. In addition, the dicliptera chinensis polysaccharide can reduce the activity or contents of an end products-peptide (AGE-P),glycosylated hemoglobin (HbAlc), total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C) and renal aldose reductase (AR) of diabetic ratserum glycosylation and increase the content of liver glycogen and high-density lipoprotein (HDL)-C), it is indicated that the dicliptera chinensis polysaccharide achieves the effect of suppressing diabetes complicationsby inhibiting liver and kidney lesions and improving a blood lipid environment. The experiment proves that the dicliptera chinensis polysaccharide has the good effect of preventing and treating the diabetes and the diabetes complications, new fields are explored for the medicinal value of the dicliptera chinensis polysaccharide through the new application, and the dicliptera chinensis polysaccharidehas an important application value and economic benefits.

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