The invention discloses a hydrophobic fluorinated polyurethane coating. The hydrophobic fluorinated polyurethane coating is a compound shown in the formula. In the formula, R1 represents CF3(CF2)7CH2CH3, R2 represents a group shown in the description, m represents an integer of 2-20 and n represents an integer of 2-20. Diphenyl methane diisocyanate (MDI) is modified by perfluoroalkyl alcohol so that a fluorine element is introduced and thus the problem that direction use of a halide such as fluorinated isocyanate causes poor material flexibility is solved. Through control of an MDI addition method in the reaction process, a hydrophilic group -CH2OH at the tail end can fully react as much as possible so that a hydrophobic group -COOCH3 is used as a tail end group and polyurethane hydrolysis resistance is improved.