The invention discloses an automobile wheel separation safety protection device. The automobile wheel separation safety protection device comprises a disc-shaped installation disc and further comprises a limiting pin. The diameter of the disc-shaped installation disc is smaller than that of an automobile wheel. The disc-shaped installation disc is installed on an axle of the inner side of the automobile wheel and close to the automobile wheel and can rotate round a rotary shaft of the automobile wheel. A plurality of support blocks are arranged in the circumferential direction of the installation disc symmetrically, and each support block is connected with the installation disc through an elastomer. Under elastic force of the elastomers, the support blocks can stretch and contract elastically in the radial direction of the installation disc. The limiting pin is arranged between the automobile wheel and the installation disc. One end of the limiting pin is connected with the automobile wheel. The other end of the limiting pin is inserted into a sliding groove of the installation disc and used for limiting displacement of the support blocks in the radial direction of the installation disc when the automobile wheel is not separated from an automobile. Through the automobile wheel separation safety protection device, when an accident occurs to the automobile, the automobile can still keep balance and travel stably after the automobile wheel is separated from the automobile.