The invention discloses a sealing structure between a front door upper angle plate and a window frame of an automobile. The sealing structure comprises the front door upper angle plate and an upper window frame section welded with the front door upper angle plate, wherein a sealing bracket is arranged at a hole formed between the front door upper angle plate and the upper window frame section and is welded and fixed on a groove bottom surface of the front door upper angle plate through a welding face of the sealing bracket, and the sealing face of the sealing bracket blocks the hole. The sealing structure can improve the wind noise preventive performance of the automotive door and improve the riding comfort.