The invention discloses a traditional Chinese medicine compound preparation for treating atherosclerosis and a preparation method thereof. The traditional Chinese medicine compound preparation is prepared from the following active pharmaceutical ingredients in parts by weight: 2-12 parts of houttuynia cordata extract, 2-12 parts of platycodon grandiflorum extract, 2-12 parts of seaweed stone extract, 5-15 parts of rheum officinale extract, 5-15 parts of turmeric extract, 10-20 parts of safflower extract, 10-20 parts of Chinese angelica extract and 10-20 parts of peach seed extract, wherein the extracts are obtained by water extraction or ethanol extraction and then filtration, centrifugation, concentration, drying and grinding. The invention provides a traditional Chinese medicine compound preparation for treating atherosclerosis and a preparation method thereof. The traditional Chinese medicine compound preparation is safe without side effects; through the compatibility of multiple active pharmaceutical ingredients, the traditional Chinese medicine compound preparation takes effect according to multiple action mechanisms, generates a synergistic effect among multiple functions, effectively acts on the organism and realizes a remarkable treatment effect; and moreover, in the preparation method, the production cost is low, and the method is simple and easy to operate.