The invention discloses a 4-carbamate-3-methoxy cinnamate aminoalkyl amide compound and a preparation method and application thereof. This compound is used to treat neurodegenerative diseases, including, but not limited to, vascular dementia, Alzheimer's disease, Parkinson's disease, Huntington's disease, HIV related dementia, multiple sclerosis, progressive amyotrophic lateral sclerosis, neuropathic pain, glaucoma and other neurodegenerative diseases.