The invention relates to the field of automobile damping elements, particularly a variable-inertia-passage-section hydraulic bushing. The bushing comprises a metal outer sleeve, a metal framework, a metal inner sleeve, a nylon stop block, liquid chambers, a rubber main spring and a two-way valve, wherein the metal outer sleeve is sheathed on the metal framework and forms an interference fit; the metal framework is sheathed on the external surface of the rubber main spring and integrally formed with the rubber main spring by sulfurization, and the metal inner sleeve is fixedly connected with the nylon stop block; the metal inner sleeve is integrally formed with the internal surface of the rubber main spring by sulfurization; and both ends of the rubber main spring are symmetrically provided with the two liquid chambers which are connected through an oblique inertia channel. According to the variable-inertia-passage-section hydraulic bushing, the two-way openable valve with pressure-dependent opening is added to the traditional hydraulic bushing, thereby ensuring favorable damping and noise reduction functions within a wide frequency range. Compared with other inventions, the variable-inertia-passage-section hydraulic bushing is more space-saving. The bushing is applicable to different vehicle models, and thus, has favorable universality.