The invention discloses an optical chip and inertial sensor integrated device and a manufacture method thereof. The optical areas of optical chips face a PCB; the pins of the optical chips are welded on the welding disc of the PCB by plating solder balls; an optical window corresponding to the optical chip is also formed in the PCB. The integrated device also comprises a transmitting part covering the optical window, wherein an inertial sensor chip is fixedly arranged on one side, far from the PCB, of each optical chip; the outer sides of the optical chips and the inertial sensor chip are provided with a non-transmitting plastic package body; the non-transmitting plastic package body can be used for achieving plastic package of the optical chips and the inertial sensor chip together on the PCB. According to the integrated device disclosed by the invention, the inertial sensor chip and the optical chips, which are both different in structure and principle, can be integrated in a same package structure, so that the package size of the whole integrated device is greatly reduced.