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发明公开
CN105486866A microRNA在制备诊断宫颈癌或其癌前病变的试剂盒中的应用 有权

microRNA在制备诊断宫颈癌或其癌前病变的试剂盒中的应用
摘要：
本发明涉及microRNA在制备诊断宫颈癌或其癌前病变的试剂盒中的应用。首次揭示了miR-375和miR-424在宫颈癌或其癌前病变的组织或细胞内明显低表达，且这种低表达与宫颈癌或其癌前病变存在明显的相关性。本发明还提供了测定miR-375和/或miR-424的存在量的宫颈癌或其癌前病变的诊断方法和试剂盒。
摘要（英）：

The invention relates to an application of microRNA in preparation of a kit for diagnosis of cervical carcinoma or precancerous lesions. According to the invention, obvious low expression of miR-375 and miR-424 in tissues and cells of cervical carcinoma or precancerous lesions is revealed, and the low expression is obviously relative to the cervical carcinoma or precancerous lesions. The invention also provides a cervical carcinoma or precancerous lesions diagnosis method and the kit for determining existence amount of miR-375 and/or miR-424.

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