The invention discloses a high selectivity methanol to durene catalyst and a preparation method thereof. The methanol to durene catalyst is characterized in that a nanometer NaZSM-5 molecular sieve is utilized by a catalyst precursor, an HZSM-5 molecular sieve is obtained after alkali treatment and ammonia exchange, the molecular sieve, a binding agent and a pore-forming agent are subjected to extrusion molding according to certain mass ratio, and the finished catalyst is obtained through hydro-thermal treatment. The catalyst has rich mesoporous structures at the positions of 3-5 nm, 7-20 nm and 20-40 nm, the total pore volume is 0.38-0.45 ml/g, and the specific surface area is 310-340 m<2>/g. The catalyst is utilized in a methanol to durene reaction process, the yield coefficient of the durene is 7-11%, and the selectivity of the durene in C10 arene is 90-99.9%.