The invention discloses a full-automatic hospital telephone follow-up method and a telephone device thereof. The telephone device comprises a hospital follow-up management server, a hospital information system, a recording telephone, a voice recognition server, a voice synthesis server and an information database. Due to the information means and design of hardware equipment, all follow-up process are integrated through the existing mature hospital information system, the recording telephone technology, the voice recognition technology, the voice synthesis technology, the database technology and the like; a function of full-automatically following up patients through a telephone can be realized; and the method disclosed by the invention can be applied to following up patients through a hospital telephone.