The invention relates to the field of medicines and nutrition and health food, and particularly discloses a sturgeon compound preparation and a preparation process thereof. The sturgeon compound preparation comprises the following components in parts by weight: 50-100 parts of sturgeon powder, 0-300 parts of sturgeon oil, raw materials 1 of 10-20 parts of microcrystalline cellulose, 20-50 parts of metal ion calcium, 1-5 parts of metal ion iron, 1-2 parts of metal ion zinc, 0.5-1.0 part of metal ion magnesium and 0.001-0.005 part of metal ion selenium, and raw materials 2 of 0.00001-0.00004 part of vitamin A, 0.00002-0.00006 part of a vitamin B group, 0.000001-0.000004 part of vitamin D, 0.00003-0.00008 part of vitamin E and 0.0003-0.0005 part of vitamin C. A method for preparing the sturgeon compound preparation into tablets, granules, capsules or powder comprises the steps of grinding, mixing, granulation formation, tabletting formation and the like. Raw materials of parts of sturgeon are fully and effectively utilized, the utilization ratio of sturgeon is improved, the components in the formula of the product are matched, balanced and comprehensive nutrients of the product are ensured, the additive amount of sturgeon oil and the process are optimized, the product quality is uniform, and digestive absorption by human is facilitated.