The present invention discloses an instant hypsizygus marmoreus soy protein powder which uses the fresh hypsizygus marmoreus or hypsizygus marmoreus leftover materials as main raw materials. The raw materials are subjected to washing, crushing, freezing, homogenizing for cell wall breaking, centrifugal separation, ultrafiltration concentration, and vacuum freeze-drying or spray drying, and the obtained materials are mixed with soy protein powder in proportion, and packaged to obtained the instant hypsizygus marmoreus soy protein powder. The instant hypsizygus marmoreus soy protein powder opens up a new way for the deep processing application of the hypsizygus marmoreus and expands application ranges of the market. The instant hypsizygus marmoreus soy protein powder is rich in hypsizygus marmoreus polysaccharides, can be consumed daily, and can enhance immunity, regulate blood pressure and lipid, clear liver and improve eyesight, and prevent and prevent against cancer.