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Invention Grant
CN104902764B 源自柑橘类的川陈皮素和橘皮素含有物的制造方法以及由此获得的川陈皮素和橘皮素含有物 有权

源自柑橘类的川陈皮素和橘皮素含有物的制造方法以及由此获得的川陈皮素和橘皮素含有物
Abstract:
本发明的目的是提供一种安全性、经济性以及工业化方面优异的以高浓度含有川陈皮素和橘皮素的级分的制造方法。所述目的通过以下制造川陈皮素和橘皮素含有物的方法以及通过该方法制造的川陈皮素和橘皮素高浓度含有物而得以实现：(1‑1)以热水处理柑橘类，获得热水处理产物的步骤；(1‑2)干燥所述热水处理产物，获得干燥产物的步骤；(1‑3)以可溶解川陈皮素和橘皮素的溶剂，对所述干燥产物进行处理，获得川陈皮素和橘皮素溶解产物的步骤；(3)通过对所述川陈皮素和橘皮素溶解产物进行浓缩和/或干燥，获得川陈皮素和橘皮素浓缩产物的步骤；以及(4)使用稀碱对所述川陈皮素和橘皮素浓缩产物进行处理，获得作为不溶性成分的川陈皮素和橘皮素含有物的步骤。
Abstract(English):

The object of the invention is to provide a method of manufacturing a fraction containing nobiletin and tangeretin at high concentrations, which is excellent in terms of safety, economic efficiency, and the potential for industrialization. The object is achieved by a method of manufacturing a composition containing nobiletin and tangeretin, comprising (1-1) a step of treating citrus fruit with hot water to obtain a hot water-treated product; (1-2) a step of drying the hot water-treated product to obtain a dried product; (1-3) a step of treating the dried product with a solvent capable of dissolving nobiletin and tangeretin to obtain a nobiletin and tangeretin solution; (3) a step of concentrating and/or drying the nobiletin and tangeretin solution to obtain a nobiletin and tangeretin concentrate; and (4) a step of treating the nobiletin and tangeretin concentrate with a dilute alkali to obtain a composition containing nobiletin and tangeretin as an insoluble component, and by a composition containing nobiletin and tangeretin at high concentrations manufactured by the method.

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