The invention belongs to the technical field of production of milk products, and discloses a preparation method of a cheese with whey. For shortening a complex technological process and avoiding loss of a nutrient in milk, namely whey, a preparation method of a soft cheese with whey is invented by taking whole milk powder and soya-bean milk as the main raw materials. Found from trial production, if a general natural milk product is replaced by soya-bean milk, namely general soybean milk powder, a cheese product having good character and mouth feel can also be obtained without discharging whey; the prepared product has flavours and textures similar to those of fresh soft cheeses, such as a quark cheese and a cottage cheese; the soft cheese is flat and smooth on surface, fine in texture and free from whey separation; and furthermore, the organoleptic quality is steady in the guarantee period.