知搜-全球专利检索

  1. 登录
  2. 注册
发明公开
CN104059984A 胆囊结石和胆囊息肉诊断试剂盒及CR2基因在其制备中的用途 有权 转让 许可 质押

  • 专利标题： 胆囊结石和胆囊息肉诊断试剂盒及CR2基因在其制备中的用途
  • 专利标题（英）： Gallstone and gallbladder polyp diagnostic kit and application of CR2 genes in manufacturing process of gallstone and gallbladder polyp diagnostic kit
  • 申请号： CN201410315636.5
    申请日： 2014-07-04
  • 公开(公告)号： CN104059984A
    公开(公告)日： 2014-09-24
  • 发明人: 杨承刚 , 宋宏涛 , 边洋 , 孙耀兰
  • 申请人： 杨承刚
  • 申请人地址： 北京市海淀区善缘街1号2层3-103
  • 专利权人： 杨承刚
  • 当前专利权人： 青岛泱深生物医药有限公司
  • 当前专利权人地址： 北京市海淀区善缘街1号2层3-103
  • 主分类号： C12Q1/68
  • IPC分类号： C12Q1/68
胆囊结石和胆囊息肉诊断试剂盒及CR2基因在其制备中的用途
摘要：
本发明公开了CR2基因在制备诊断胆囊结石和胆囊息肉的试剂盒中的用途。本发明利用高通量测序技术筛选出CR2基因在胆囊结石中表达下调，在胆囊息肉中表达上调，并使用荧光实时定量PCR方法验证了上述结论，据此，本发明还公开了一种诊断胆囊结石和胆囊息肉的试剂盒以及利用该试剂盒诊断胆囊结石和胆囊息肉的方法。本发明一方面为研究胆囊息肉和胆囊结石的分子机理提供新的思路，另一方面为早期诊断胆囊结石和胆囊息肉提供了更为灵敏的诊断试剂盒。
摘要（英）：

The invention discloses application of CR2 genes in the manufacturing process of a gallstone and gallbladder polyp diagnostic kit. The application is characterized in that it is screened that expression of the CR2 genes in the gallstone is reduced, and expression of the CR2 genes in the gallbladder polyp is increased with the high-throughput sequencing technology, and the conclusion is verified with the fluorescent real-time quantitative PCR method. In this way, the invention further discloses the gallstone and gallbladder polyp diagnostic kit and a method for diagnosing the gallstone and the gallbladder polyp through the kit. By means of the application, the gallstone and gallbladder polyp diagnostic kit and the method, a new thought is provided for researching molecular mechanisms of the gallbladder polyp and the gallstone, and the early diagnosis of the gallstone and the gallbladder polyp are sensitive.

公开/授权文献
0/0