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发明公开
CN103589795A 一种检测与肺癌易感性及化疗敏感性相关基因的多态性的试剂盒及其应用 失效 - 权利终止 转让

一种检测与肺癌易感性及化疗敏感性相关基因的多态性的试剂盒及其应用
摘要：
本发明公开了一种检测与肺癌易感性及化疗敏感性相关基因的多态性的试剂盒，该试剂盒中含有检测WISP1基因C3290T位点的探针和引物，所述探针和引物能与WISP1基因C3290T位点前后的基因序列特异性结合并扩增出包含WISP1基因C3290T位点的基因序列。本发明是基于Taqman分型方法检测基因多态性的试剂盒，该试剂盒能准确、快速、简便地检测与非小细胞肺癌铂类药物化疗敏感性相关的基因位点（WISP1基因C3290T多态性）。
摘要（英）：

The invention discloses a kit for detecting the polymorphism of a gene related to munity of lung cancer and chemosensitivity. The kit comprises a probe and a primer which are used for detecting a locus of a WISPI gene C3290T, and the probe and the primer can also be specifically combined with gene sequences in the front or back of the locus of the WISPI gene C3290T and amplify a gene sequence containing the locus of the WISPI gene C3290T. The kit is a kit for detecting the gene polymorphism on the basis of a Taqman typing method, and can accurately, rapidly and conveniently detect the genetic locus (the polymorphism of the WISPI gene C3290T) related to chemosensitivity of the platinum drugs for the non-small cell lung cancer.

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