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发明公开
CN103298775A 新型二羟基苯衍生物和以它们作为有效成分的抗原虫剂 失效 - 权利终止 转让

新型二羟基苯衍生物和以它们作为有效成分的抗原虫剂
摘要：
下述的新型化合物对预防或治疗由原虫类引起的疾病是有用的。使用式(I)所示的化合物、它们的光学异构体以及它们的药学上可接受的盐中的1种或2种以上。式(I)中，X表示氢原子或卤原子，R1表示氢原子，R2表示氢原子或碳原子数为1～7的烷基，R3表示-CHO、-C(=O)R5、-COOR5(式中，R5表示碳原子数为1～7的烷基)、-CH20H或-COOH，R4表示末端的碳上和/或非末端的碳上具有各种取代基的碳原子数为1～16的烷基、末端的碳上和/或非末端的碳上具有各种取代基的碳原子数为2～16的烯基、或者末端的碳上和/或非末端的碳上具有各种取代基的碳原子数为2～16的炔基。
摘要（英）：

Novel compounds represented by formula (I) are useful for preventing or treating diseases caused by protozoans. Use is made of one or more members selected from among compounds represented by formula (I), optical isomers thereof and pharmaceutically acceptable salts of the same. In formula (I): X represents a hydrogen atom or a halogen atom; R<1> represents a hydrogen atom; R<2> represents a hydrogen atom or a C1-7 alkyl group; R<3> represents -CHO, -C(=O)R5, -COOR5 [wherein R<5> represents a C1-7 alkyl group], -CH2OH or -COOH; and R<4> represents a C1-16 alkyl group having various substituent(s) on a terminal carbon atom and/or a non-terminal carbon atom, a C2-16 alkenyl group having various substituent(s) on a terminal carbon atom and/or a non-terminal carbon atom, or a C2-16 alkynyl group having various substituent(s) on a terminal carbon atom and/or a non-terminal carbon atom.

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