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发明公开
CN102212109A 从骨肽注射剂中分离的骨多肽化合物及其应用 有权 许可 转让

从骨肽注射剂中分离的骨多肽化合物及其应用
摘要：
本发明涉及从动物骨提取有效部位后制成的注射剂中分离的骨多肽化合物，具体讲，涉及从骨肽注射剂中分离的骨多肽化合物、以及其制备方法和应用。其中，骨肽注射剂包括粉针、水针和输液。骨多肽化合物A、B、C、D、E的氨基酸序列分别为SEQ ID NO：1、SEQ IDNO：2、SEQ ID NO：3、SEQ ID NO：4、SEQ ID NO：5。本发明还涉及含有骨多肽化合物的制剂。本发明还涉及所述的骨多肽化合物在制备抗炎、镇痛、促进骨折愈合药物中的应用。经过动物实验及临床试验证实，本发明的骨多肽化合物具有良好的效果。
摘要（英）：

The invention relates to a bone polypeptide compound separated from an ossotide injection which is prepared by extracting an active component from animal bones, in particular to the bone polypeptide compound separated from the ossotide injection, a preparation method thereof and application thereof. The ossotide injection comprises a powder injection, a water injection and an infusion solution. The amino sequences of bone polypeptide compounds A, B, C and D are SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4 and SEQ ID NO:5 respectively. The invention relates to a preparation containing the bone polypeptide compound and the application of the bone polypeptide compound to the preparation of medicaments for resisting inflammation, relieving pains and promoting fracture healing. Animal experiments and clinical tests find that the bone polypeptide compound has a good effect.

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