The invention discloses a new compound of (2R)-1,7,7-trimethyl bicylo[2.2.1]heptanes-2-group-4-(4,5-dihydro-3-methyl-5-oxo parazole-1-group)benzoic acid, salt thereof, a preparation method thereof, pharmaceutical application thereof in cerebral ischemia injury protection, and a medicinal composition comprising the compound or the salt of the compound. The new compound is generated by reacting 4-(4,5-dihydro-3-methyl-5-oxo parazole-1-group)benzoic acid with (+)-2-borneol, wherein the 4-(4,5-dihydro-3-methyl-5-oxo parazole-1-group)benzoic acid is a structural analogue of edaravone; and the (+)-2-borneol has definite cerebral ischemia injury protection effect. A test proves that the new compound achieves the cerebral ischemia injury protection effect by improving the vitality of nerve cells so as to obviously improve a neurologic deficit symptom and shorten a cerebral infarction area to reduce cerebral injury degree, and has the potential of being developed into cerebral ischemia protection medicaments or antithrombotic medicaments.