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发明公开
CN102127149A 心肌特异性同源盒部分多肽及其应用 失效 - 权利终止

心肌特异性同源盒部分多肽及其应用
摘要：
本发明公开了一种心肌特异性同源盒部分多肽及其应用。本发明的心肌特异性同源盒部分多肽，其氨基酸序列为序列表中的序列1。所述多肽与载体蛋白偶联可形成复合蛋白。所述载体蛋白可以为匙孔血蓝蛋白或牛血清白蛋白。所述复合蛋白和免疫佐剂混合的混合物可作为免疫原。本发明的免疫原免疫动物获得了较高效价的免疫血清，经ELISA检验效价高于1∶62500，免疫血清能在细胞水平上检测禽源心肌特异性同源盒的表达。
摘要（英）：

The invention discloses a myocardial specificity homeobox part polypeptide and application thereof. The amino acid sequence of the myocardial specificity homeobox part polypeptide is a sequence I in a sequence table. The polypeptide and carrier protein are coupled to form composite protein. The carrier protein can be keyhole limpet hemocyanin or bovine serum albumin. A mixture of the composite protein and an immunologic adjuvant can be used as immunogen. Immune serum with higher valence is obtained by immunizing an animal with the immunogen, the valence is higher than 1: 62500 through ELISA (Enzyme-Linked Immuno Sorbent Assay) detection and the immune serum can detect the expression of an avian myocardial specificity homeobox on the cell level.

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