The invention relates to a synthesis method of antioxidant 1076 using solid base catalyst. The 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate and the octadecanol are used as raw materials which are subjected to the interesterification reaction in the presence of a solid base catalyst to obtain the product of antioxidant 1076 with the purity more than or equal to 97.5% and the yield more than or equal to 85%. Compared with the prior art, the method provided by the invention utilizes the prepared solid base catalyst, thus the catalysis effect is improved, and the quality of obtained products is stable; in addition, the solid base catalyst is recyclable and environmental friendly, and the process operation is safe and convenient, therefore the method is suitable for the industrialized and mass production.