知搜-全球专利检索

  1. 登录
  2. 注册
发明公开
CN101932311A 微粒及其药物组合物 有权

微粒及其药物组合物
摘要：
本发明涉及一种由含有两亲性聚合物及亲水性活性物质的亲水性活性物质含有粒子附聚而成的微粒，其中，所述两亲性聚合物由聚(羟基酸)的疏水性片段和多糖或聚乙二醇的亲水性片段组成，所述微粒能有效地封入亲水性活性物质，并能在生物体内以合适的速度释放亲水性活性物质，因此作为DDS制剂是有用的。
摘要（英）：

Microparticles useful as DDS preparations are made by associating amphipathic polymers made of hydrophobic poly(hydroxy acid) segments and hydrophilic polysaccharide or polyethylene glycol segments having hydrophilic active substance-containing particles made by including a hydrophilic active substance that can efficiently seal in the hydrophilic active substance and that can release the hydrophilic active substance into the body at an appropriate rate.

公开/授权文献
0/0